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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2004-11-10
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pubmed:abstractText |
Antibodies directed toward citrullinated proteins (e.g., anti-cyclic citrullinated peptide antibodies) are highly specific for rheumatoid arthritis (RA) and are produced locally at the site of inflammation. Although the presence of citrullinated proteins in rheumatoid synovium has been described in the literature, it is uncertain whether their presence is specific for RA. The present study was undertaken to investigate this.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3485-94
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15529392-Adult,
pubmed-meshheading:15529392-Aged,
pubmed-meshheading:15529392-Aged, 80 and over,
pubmed-meshheading:15529392-Antibodies,
pubmed-meshheading:15529392-Arthritis, Rheumatoid,
pubmed-meshheading:15529392-Case-Control Studies,
pubmed-meshheading:15529392-Citrulline,
pubmed-meshheading:15529392-Female,
pubmed-meshheading:15529392-Humans,
pubmed-meshheading:15529392-Immunoglobulins,
pubmed-meshheading:15529392-Immunohistochemistry,
pubmed-meshheading:15529392-Joint Diseases,
pubmed-meshheading:15529392-Male,
pubmed-meshheading:15529392-Middle Aged,
pubmed-meshheading:15529392-Peptides, Cyclic,
pubmed-meshheading:15529392-Staining and Labeling,
pubmed-meshheading:15529392-Synovial Membrane
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pubmed:year |
2004
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pubmed:articleTitle |
The presence of citrullinated proteins is not specific for rheumatoid synovial tissue.
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pubmed:affiliation |
Department of Biochemistry 161, Radboud University Nijmegen, NL-6500 HB Nijmegen, The Netherlands. e.vossenaar@ncmls.ru.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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