Linked Life Data

15527687

Source:http://linkedlifedata.com/resource/pubmed/id/15527687

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2004-11-5
pubmed:abstractText
Numerous studies performed in the past decade have shown that increased pulse pressure, an indicator of arterial stiffening, is associated with adverse clinical outcomes. Research is now focused on better defining the anatomic and physiologic determinants of increased pulse pressure. Early work considered aortic stiffening to be a passive, irreversible consequence of aging that was accelerated by hypertension. Recent studies suggest that aortic stiffening is dynamic and reversible and that abnormalities in aortic function may play a primary role in the pathogenesis of hypertension. This review summarizes current work on the genesis of increased pulse pressure and abnormal pulsatile load in hypertension, and underscores areas for future research.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1522-6417
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
436-41
pubmed:dateRevised
2006-7-12
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Arterial stiffness and wave reflection in hypertension: pathophysiologic and therapeutic implications.
pubmed:affiliation
Cardiovascular Engineering, Inc., 327 Fiske Street, Holliston, MA 01746, USA. GaryFMitchell@mindspring.com
pubmed:publicationType
Journal Article, Review