Source:http://linkedlifedata.com/resource/pubmed/id/15522167
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2004-11-3
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pubmed:abstractText |
Many studies showed that high expression of Cyclin E promotes cell proliferation, but contrary data was also reported that cell proliferation didn't decrease with low expression of Cyclin E. In addition, we observed that many tumor cells have strong capability of proliferation with low expression of Cyclins, including Cyclin E. This study was to analyze effect of reduced Cyclin E threshold on proliferation of acute lymphocyte leukemia cell line MOLT-4 to explain the above phenomena.
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pubmed:language |
chi
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1000-467X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1244-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15522167-Caffeine,
pubmed-meshheading:15522167-Cell Line, Tumor,
pubmed-meshheading:15522167-Cell Proliferation,
pubmed-meshheading:15522167-Cyclin E,
pubmed-meshheading:15522167-Down-Regulation,
pubmed-meshheading:15522167-G1 Phase,
pubmed-meshheading:15522167-Gene Expression Regulation, Leukemic,
pubmed-meshheading:15522167-Humans,
pubmed-meshheading:15522167-Ki-67 Antigen,
pubmed-meshheading:15522167-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:15522167-Proliferating Cell Nuclear Antigen
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pubmed:year |
2004
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pubmed:articleTitle |
[Promotive effect of decreased cyclin E threshold on cell proliferation].
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pubmed:affiliation |
Center of Gastroenterological Surgery/Cancer Research Institute, Tongji Hospital, Tongji Medical College, University of Huazhong Science and Technology, Wuhan, Hubei 430 030, P.R. China.
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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