rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5A
|
pubmed:dateCreated |
2004-11-2
|
pubmed:abstractText |
Chromosomal aberrations in breast tumors from BRCA1 and BRCA2 germ-line mutation carriers are considerably more frequent than what is seen in sporadic breast tumors. According to Comparative Genomic Hybridisation analysis (CGH), deletions on chromosome 4 are one of the most frequent events in BRCA1-associated tumors, suggesting inactivation of specific tumor suppressor genes.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
|
pubmed:author |
pubmed-author:AgnarssonBjarni ABA,
pubmed-author:ArasonAdalgeirA,
pubmed-author:BarkardottirRosa BRB,
pubmed-author:BorgAkeA,
pubmed-author:EerolaHannaleenaH,
pubmed-author:EgilssonValgardurV,
pubmed-author:HeikkiläPäiviP,
pubmed-author:JohannesdottirGudrunG,
pubmed-author:JohannsdottirHrefna KHK,
pubmed-author:JohannssonOskar T HOT,
pubmed-author:NevanlinnaHeliH,
pubmed-author:OlssonHakanH
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pubmed:issnType |
Print
|
pubmed:volume |
24
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2681-7
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15521105-Breast Neoplasms,
pubmed-meshheading:15521105-Chromosomes, Human, Pair 4,
pubmed-meshheading:15521105-DNA, Neoplasm,
pubmed-meshheading:15521105-Female,
pubmed-meshheading:15521105-Gene Deletion,
pubmed-meshheading:15521105-Genes, BRCA1,
pubmed-meshheading:15521105-Genes, BRCA2,
pubmed-meshheading:15521105-Germ-Line Mutation,
pubmed-meshheading:15521105-Humans,
pubmed-meshheading:15521105-Loss of Heterozygosity,
pubmed-meshheading:15521105-Nucleic Acid Hybridization
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pubmed:articleTitle |
Deletions on chromosome 4 in sporadic and BRCA mutated tumors and association with pathological variables.
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pubmed:affiliation |
Department of Pathology, Landspitali-University Hospital by Hringbraut, Reykjavik, Iceland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|