Source:http://linkedlifedata.com/resource/pubmed/id/15507715
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
2004-10-27
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| pubmed:abstractText |
Latent membrane protein 2A (LMP-2A) of Epstein-Barr virus (EBV) mimics a constitutively active B-cell receptor (BCR) and plays a key role in viral latency and EBV pathogenesis. By functioning as a BCR mimic, LMP-2A drives B-cell development, resulting in the bypass of normal B-cell developmental checkpoints. To assess the function of LMP-2A, we have utilized a colony formation assay for the progenitor B cells that uses the B-cell proliferation factor IL-7.
|
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:issn |
1064-3745
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
292
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
279-84
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| pubmed:meshHeading |
pubmed-meshheading:15507715-Animals,
pubmed-meshheading:15507715-B-Lymphocytes,
pubmed-meshheading:15507715-Biological Assay,
pubmed-meshheading:15507715-Bone Marrow Cells,
pubmed-meshheading:15507715-Cell Differentiation,
pubmed-meshheading:15507715-Cell Division,
pubmed-meshheading:15507715-Interleukin-7,
pubmed-meshheading:15507715-Mice,
pubmed-meshheading:15507715-Viral Matrix Proteins
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| pubmed:year |
2005
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| pubmed:articleTitle |
Pre-B-cell colony formation assay.
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| pubmed:affiliation |
Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
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| pubmed:publicationType |
Journal Article
|