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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2004-10-26
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pubmed:abstractText |
Human urotensin II (hU-II) is a cyclic peptide highly expressed in cardiac tissues and blood vessels. hU-II is a potent vasoconstrictor. Recent studies indicate that urotensin II participates in myocardial remodeling after injury. This study was designed to study the role of hU-II in the expression of matrix metalloproteinase-1 (MMP-1) and collagen-1 in human umbilical vein endothelial cells (HUVECs) and underlying intracellular signaling mechanisms.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0160-2446
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
577-81
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15505495-Cells, Cultured,
pubmed-meshheading:15505495-Collagen Type I,
pubmed-meshheading:15505495-Dose-Response Relationship, Drug,
pubmed-meshheading:15505495-Down-Regulation,
pubmed-meshheading:15505495-Endothelial Cells,
pubmed-meshheading:15505495-Endothelium, Vascular,
pubmed-meshheading:15505495-Flavonoids,
pubmed-meshheading:15505495-Humans,
pubmed-meshheading:15505495-MAP Kinase Signaling System,
pubmed-meshheading:15505495-Matrix Metalloproteinase 1,
pubmed-meshheading:15505495-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:15505495-Phosphorylation,
pubmed-meshheading:15505495-Time Factors,
pubmed-meshheading:15505495-Umbilical Veins,
pubmed-meshheading:15505495-Up-Regulation,
pubmed-meshheading:15505495-Urotensins
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pubmed:year |
2004
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pubmed:articleTitle |
Human urotensin II modulates collagen synthesis and the expression of MMP-1 in human endothelial cells.
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pubmed:affiliation |
Renhe Hospital, Shanghai, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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