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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2004-10-26
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pubmed:abstractText |
Verteporfin photodynamic therapy (PDT) is the most effective treatment for age-related macular degeneration, using laser activation of a photosensitizing dye to achieve closure of choroidal neovascularization. Although PDT preferentially affects pathologic vessels, it can also cause collateral damage to the overlying retina. In the current study, it was found that the neuroprotective agent brain-derived neurotrophic factor (BDNF) reduces this retinal damage.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4190-6
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15505074-Animals,
pubmed-meshheading:15505074-Brain-Derived Neurotrophic Factor,
pubmed-meshheading:15505074-Choroid,
pubmed-meshheading:15505074-Electroretinography,
pubmed-meshheading:15505074-Fluorescein Angiography,
pubmed-meshheading:15505074-Fluorescence,
pubmed-meshheading:15505074-Neuroprotective Agents,
pubmed-meshheading:15505074-Photochemotherapy,
pubmed-meshheading:15505074-Photoreceptor Cells, Vertebrate,
pubmed-meshheading:15505074-Photosensitizing Agents,
pubmed-meshheading:15505074-Porphyrins,
pubmed-meshheading:15505074-Rats,
pubmed-meshheading:15505074-Rats, Inbred BN,
pubmed-meshheading:15505074-Retina
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pubmed:year |
2004
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pubmed:articleTitle |
BDNF reduces the retinal toxicity of verteporfin photodynamic therapy.
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pubmed:affiliation |
Department of Ophthalmology, University of California, San Francisco, 94143-0730, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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