Linked Life Data

15503143

Source:http://linkedlifedata.com/resource/pubmed/id/15503143

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2005-1-25
pubmed:abstractText
Broken chromosome ends are believed to be capped by a terminal protein complex, and can be maintained in Drosophila melanogaster for many generations. We investigated whether the vicinity of a chromosome end affected P element mobilization and the subsequent repair of the resulting DNA lesion. High levels of P element excision were observed when at least 5 kb of DNA was located between the P element and the end of the chromosome, but recovery of chromosomes from which the P element had been excised was greatly reduced when the chromosome end was positioned less than 5 kb away from the original P element insertion site. Moreover, when the P element was mobilized in terminal deficiency ( y (TD )) alleles, excision events were accompanied by deletions of sequences originally located distal to the P element.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1617-4615
pubmed:author
pubmed:issnType
Print
pubmed:volume
272
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
512-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
The vicinity of a broken chromosome end affects P element mobilization in Drosophila melanogaster.
pubmed:affiliation
Department of the Control of Genetic Processes, Institute of Gene Biology, Russian Academy of Sciences, 119334, Moscow, Russian Federation.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't