Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2004-10-25
pubmed:abstractText
In heart transplantation, myocardial apoptosis during hypothermic storage contributes to graft dysfunction. On the other hand, hepatocyte growth factor (HGF) has been reported to be an antiapoptotic factor in the heart. Therefore, we assessed whether the administration of recombinant human HGF (rh-HGF) prevents apoptosis in the prolonged preserved myocardium, resulting in an improvement in the cardiac function of the graft.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0041-1337
pubmed:author
pubmed:issnType
Print
pubmed:day
27
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1153-8
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:15502712-Animals, pubmed-meshheading:15502712-Apoptosis, pubmed-meshheading:15502712-Caspase 3, pubmed-meshheading:15502712-Caspases, pubmed-meshheading:15502712-Cryopreservation, pubmed-meshheading:15502712-Heart, pubmed-meshheading:15502712-Hepatocyte Growth Factor, pubmed-meshheading:15502712-Humans, pubmed-meshheading:15502712-In Situ Nick-End Labeling, pubmed-meshheading:15502712-Myocardial Reperfusion, pubmed-meshheading:15502712-Myocardium, pubmed-meshheading:15502712-Organ Preservation, pubmed-meshheading:15502712-Proto-Oncogene Proteins c-bcl-2, pubmed-meshheading:15502712-Proto-Oncogene Proteins c-met, pubmed-meshheading:15502712-Rats, pubmed-meshheading:15502712-Rats, Sprague-Dawley, pubmed-meshheading:15502712-Recombinant Proteins, pubmed-meshheading:15502712-Recovery of Function, pubmed-meshheading:15502712-Staining and Labeling, pubmed-meshheading:15502712-Time Factors, pubmed-meshheading:15502712-bcl-X Protein
pubmed:year
2004
pubmed:articleTitle
Myocardial protective effect of human recombinant hepatocyte growth factor for prolonged heart graft preservation in rats.
pubmed:affiliation
Division of Cardiovascular Surgery, Department of Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
pubmed:publicationType
Journal Article, Evaluation Studies