|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
2004-10-25
|
|
pubmed:abstractText |
Children with medulloblastoma demonstrate post-treatment neurocognitive deficits in a number of areas, including memory performance. However, there is no definitive understanding of the neuropathology underlying these functional deficits. Previous literature has reported that hippocampal integrity is crucial to the acquisition of new episodic memories. Therefore, we hypothesized that longitudinal hippocampal volume measurements are abnormal in patients with medulloblastoma and thereby provide a possible substrate for explaining memory dysfunction.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0195-6108
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright American Society of Neuroradiology
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
25
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1575-82
|
|
pubmed:dateRevised |
2008-2-14
|
|
pubmed:meshHeading |
pubmed-meshheading:15502141-Amnesia,
pubmed-meshheading:15502141-Atrophy,
pubmed-meshheading:15502141-Cerebellar Neoplasms,
pubmed-meshheading:15502141-Chemotherapy, Adjuvant,
pubmed-meshheading:15502141-Child,
pubmed-meshheading:15502141-Child, Preschool,
pubmed-meshheading:15502141-Combined Modality Therapy,
pubmed-meshheading:15502141-Female,
pubmed-meshheading:15502141-Hippocampus,
pubmed-meshheading:15502141-Humans,
pubmed-meshheading:15502141-Longitudinal Studies,
pubmed-meshheading:15502141-Magnetic Resonance Imaging,
pubmed-meshheading:15502141-Male,
pubmed-meshheading:15502141-Medulloblastoma,
pubmed-meshheading:15502141-Prognosis,
pubmed-meshheading:15502141-Radiation Injuries,
pubmed-meshheading:15502141-Radiotherapy Dosage
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Abnormal hippocampal development in children with medulloblastoma treated with risk-adapted irradiation.
|
|
pubmed:affiliation |
Division of Behavioral Medicine, St Jude Children's Research Hospital, Memphis, TN, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
