Source:http://linkedlifedata.com/resource/pubmed/id/15501985
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
20
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pubmed:dateCreated |
2004-10-25
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pubmed:abstractText |
Human T-cell leukemia virus type I (HTLV-I) can cause an adult T-cell leukemia/lymphoma (ATLL). Because ATLL is a life-threatening lymphoproliferative disorder and is resistant to chemotherapy, the establishment and enhancement of T-cell immunity to HTLV-I through the development of therapeutic vaccines could be of value. Thus, the identification of HTLV-I epitopes for both CD8(+) and CD4(+) T cells should facilitate the development of effective vaccines. Although numerous HTLV-I epitopes for CTLs have been identified, few epitopes recognized by CD4(+) helper T cells against this virus have been described.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1078-0432
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7053-62
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pubmed:dateRevised |
2011-6-7
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pubmed:meshHeading |
pubmed-meshheading:15501985-Algorithms,
pubmed-meshheading:15501985-CD4-Positive T-Lymphocytes,
pubmed-meshheading:15501985-Epitopes,
pubmed-meshheading:15501985-Human T-lymphotropic virus 1,
pubmed-meshheading:15501985-Humans,
pubmed-meshheading:15501985-Immunotherapy,
pubmed-meshheading:15501985-Leukemia-Lymphoma, Adult T-Cell,
pubmed-meshheading:15501985-Tumor Cells, Cultured,
pubmed-meshheading:15501985-Viral Envelope Proteins
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pubmed:year |
2004
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pubmed:articleTitle |
Recognition of adult T-cell leukemia/lymphoma cells by CD4+ helper T lymphocytes specific for human T-cell leukemia virus type I envelope protein.
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pubmed:affiliation |
Department of Pathology, Asahikawa Medical College, Asahikawa, Japan. hiroya@asahikawa-med.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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