Linked Life Data

15501638

Source:http://linkedlifedata.com/resource/pubmed/id/15501638

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2004-10-25
pubmed:abstractText
Hormonal integration of the reproductive system is dramatically affected by reproductive aging. The progressive loss of ovarian follicles with normal aging is accompanied by an initial decrease in inhibin B and a concomitant increase in follicle-stimulating hormone. Subsequently, inhibin A and progesterone decrease, where as estradiol levels are maintained and often increase. In the late reproductive stage, cycles remain regular whereas the early and late menopausal transition are characterized by irregular cycles and often dramatic swings in estradiol and gonadotropin levels. Studies in younger and older postmenopausal women suggest that there are age-related changes in the neuroendocrine axis that are independent of the changing ovarian hormonal milieu of the menopausal transition but may contribute to the end of reproductive life.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0889-8529
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
637-59
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Neuroendocrine physiology of the early and late menopause.
pubmed:affiliation
Harvard Medical School, Boston, MA 02114, USA. jehall@partners.org
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review