Linked Life Data

15501164

Source:http://linkedlifedata.com/resource/pubmed/id/15501164

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2004-10-25
pubmed:abstractText
Stem cells are undifferentiated cells, with the ability to self renew and to differentiate into specialised cells. Embryonic stem cells (ES) have proven to be truly pluripotent, since they are able to give derivatives of the three primitive embryonic layers. Human ES have a normal karyotype, maintain high telomerase activity, and exhibit remarkable long-term proliferative potential, providing the possibility for unlimited expansion in culture. Though human ES cell-based transplantation therapy holds great promises to successfully treat a variety of diseases (e.g., Parkinson's disease, diabetes, and heart failure) many barriers remain in the way of successful clinical trials. Less spectacular, the applications in the field of reproductive biology are also outstanding: stem cell biology will lead us to a better understanding of the cellular and molecular mechanisms of events such as infertility, failure of implantation, genomic imprinting and meiosis. The obstetrician and gynaecologist could act an important part in the production and study of embryonic stem cells. However, these data have to be integrated in the ethical and juridical background of embryonic stem cell research in France.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1297-9589
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
866-71
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
[Embryonic stem cells: a position for the obstetrician and gynaecologist. Part one].
pubmed:affiliation
Service de gynécologie-obstétrique B et médecine de la reproduction, faculté de médecine, université Montpellier-I, hôpital universitaire Arnaud-de-Villeneuve, 371, avenue du Doyen-Gaston-Giraud, 34295 Montpellier 5, France. l-reyftmann@chu-montpellier.fr
pubmed:publicationType
Journal Article, English Abstract, Review