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rdf:type |
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|
lifeskim:mentions |
|
|
pubmed:issue |
2
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|
pubmed:dateCreated |
2004-11-1
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|
pubmed:abstractText |
Selective internal radiation therapy (SIRT) with SIR-Spheres(R) is a new technique for selectively targeting high doses of radiation to tumours within the liver. The primary objectives of this randomised trial were to compare the response rate, time to progressive disease (PD), and toxicity of a regimen of systemic fluorouracil/leucovorin chemotherapy versus the same chemotherapy plus a single administration of SIR-Spheres in patients with advanced colorectal liver metastases. The trial was designed to presage a larger trial that would have survival as the primary outcome.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-4790
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pubmed:author |
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pubmed:copyrightInfo |
(c) 2004 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:day |
1
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|
pubmed:volume |
88
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
78-85
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pubmed:dateRevised |
2006-4-24
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pubmed:meshHeading |
pubmed-meshheading:15499601-Aged,
pubmed-meshheading:15499601-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:15499601-Colorectal Neoplasms,
pubmed-meshheading:15499601-Combined Modality Therapy,
pubmed-meshheading:15499601-Disease Progression,
pubmed-meshheading:15499601-Disease-Free Survival,
pubmed-meshheading:15499601-Drug Administration Schedule,
pubmed-meshheading:15499601-Female,
pubmed-meshheading:15499601-Fluorouracil,
pubmed-meshheading:15499601-Humans,
pubmed-meshheading:15499601-Leucovorin,
pubmed-meshheading:15499601-Liver Neoplasms,
pubmed-meshheading:15499601-Male,
pubmed-meshheading:15499601-Microspheres,
pubmed-meshheading:15499601-Middle Aged,
pubmed-meshheading:15499601-Quality of Life,
pubmed-meshheading:15499601-Radiotherapy Dosage,
pubmed-meshheading:15499601-Survival Rate
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|
pubmed:year |
2004
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|
pubmed:articleTitle |
Randomised phase 2 trial of SIR-Spheres plus fluorouracil/leucovorin chemotherapy versus fluorouracil/leucovorin chemotherapy alone in advanced colorectal cancer.
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pubmed:affiliation |
Mount Hospital, Western Australia, Australia.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Clinical Trial, Phase II
|
