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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2004-10-22
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pubmed:abstractText |
Dihydroartemisinin-piperaquine (DP) is a new and relatively inexpensive artemisinin-containing fixed-combination antimalarial treatment. An adult treatment course contained 6.4 mg/kg dihydroartemisinin (DHA), which is >40% lower than the level in most artemisinin-containing combinations. This raised the possibility that the efficacy of the current coformulation may not be optimal in the treatment of multidrug-resistant falciparum malaria.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-1899
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pubmed:author |
pubmed-author:AshleyElizabeth AEA,
pubmed-author:BrockmanAlanA,
pubmed-author:HutagalungRobertR,
pubmed-author:KrudsoodSrivichaS,
pubmed-author:LeowattanaWattanaW,
pubmed-author:LooareesuwanSornchaiS,
pubmed-author:McGreadyRoseR,
pubmed-author:NostenFrancoisF,
pubmed-author:PhaiphunLucyL,
pubmed-author:SrivilairitSiripanS,
pubmed-author:WhiteNicholas JNJ,
pubmed-author:WilairatanaPolratP
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
190
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1773-82
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15499533-Adolescent,
pubmed-meshheading:15499533-Adult,
pubmed-meshheading:15499533-Animals,
pubmed-meshheading:15499533-Antimalarials,
pubmed-meshheading:15499533-Artemisinins,
pubmed-meshheading:15499533-Child,
pubmed-meshheading:15499533-Child, Preschool,
pubmed-meshheading:15499533-Drug Combinations,
pubmed-meshheading:15499533-Drug Resistance, Multiple,
pubmed-meshheading:15499533-Drug Therapy, Combination,
pubmed-meshheading:15499533-Female,
pubmed-meshheading:15499533-Humans,
pubmed-meshheading:15499533-Infant,
pubmed-meshheading:15499533-Malaria, Falciparum,
pubmed-meshheading:15499533-Male,
pubmed-meshheading:15499533-Mefloquine,
pubmed-meshheading:15499533-Middle Aged,
pubmed-meshheading:15499533-Plasmodium falciparum,
pubmed-meshheading:15499533-Quinolines,
pubmed-meshheading:15499533-Sesquiterpenes,
pubmed-meshheading:15499533-Thailand
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pubmed:year |
2004
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pubmed:articleTitle |
Randomized, controlled dose-optimization studies of dihydroartemisinin-piperaquine for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand.
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pubmed:affiliation |
Shoklo Malaria Research Unit, Mae Sot, and Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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