| pubmed-article:1549575 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1549575 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:1549575 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:1549575 | lifeskim:mentions | umls-concept:C0017428 | lld:lifeskim |
| pubmed-article:1549575 | lifeskim:mentions | umls-concept:C1514586 | lld:lifeskim |
| pubmed-article:1549575 | lifeskim:mentions | umls-concept:C2745888 | lld:lifeskim |
| pubmed-article:1549575 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:1549575 | pubmed:dateCreated | 1992-4-17 | lld:pubmed |
| pubmed-article:1549575 | pubmed:abstractText | The pseudoautosomal (PA) region of the mammalian genome is the region of the X and Y chromosomes that shares extensive DNA sequence homology and is of special interest because it may play an essential role during male meiosis. We have identified three telomere-related restriction fragments from the PA region of the mouse genome, using an oligonucleotide probe composed of the mammalian telomere consensus sequence TTAGGG. PA assignment of two C57BL/6J-derived fragments was initially suggested by analysis of DNAs from progeny sired by C57BL/6J males carrying the rearranged Y chromosome, Y*: the hybridization intensity of both fragments was concordant with the sex-chromosome complement of the offspring. Further analysis indicated that both fragments were present in female and male F1, mice regardless of the sex of their C57BL/6J parent--a criterion for autosomal or PA linkage. Both fragments were closely linked to each other and located on the X chromosome distal to amelogenin (Amg)--in agreement with X or PA linkage. Confirmation of the PA derivation of these fragments was accomplished by following their segregation in a cross involving XY* males mated to DBA/2J females. A similar experiment identified a third PA-derived restriction fragment of LT/SvEi origin. Identification of PA-derived telomere-related restriction fragments will enable further genetic analysis of this region of the mouse genome. | lld:pubmed |
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| pubmed-article:1549575 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1549575 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1549575 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1549575 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1549575 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:1549575 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:1549575 | pubmed:author | pubmed-author:LeeB KBK | lld:pubmed |
| pubmed-article:1549575 | pubmed:author | pubmed-author:EicherE MEM | lld:pubmed |
| pubmed-article:1549575 | pubmed:author | pubmed-author:HallD LDL | lld:pubmed |
| pubmed-article:1549575 | pubmed:author | pubmed-author:WashburnL LLL | lld:pubmed |
| pubmed-article:1549575 | pubmed:author | pubmed-author:KingT RTR | lld:pubmed |
| pubmed-article:1549575 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1549575 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:1549575 | pubmed:volume | 89 | lld:pubmed |
| pubmed-article:1549575 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1549575 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1549575 | pubmed:pagination | 2160-4 | lld:pubmed |
| pubmed-article:1549575 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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| pubmed-article:1549575 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1549575 | pubmed:articleTitle | Telomere-related markers for the pseudoautosomal region of the mouse genome. | lld:pubmed |
| pubmed-article:1549575 | pubmed:affiliation | Jackson Laboratory, Bar Harbor, ME 04609. | lld:pubmed |
| pubmed-article:1549575 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1549575 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1549575 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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