Linked Life Data

15495513

Source:http://linkedlifedata.com/resource/pubmed/id/15495513

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
37
pubmed:dateCreated
2004-10-21
pubmed:abstractText
An amoebic liver abscess, amoebic dysentery and asymptomatic cyst passage were diagnosed in a father, a mother and one of their three children, respectively. One of the other children had been in the tropics, but only after the father's symptoms had begun. All three family members were infected with the same strain of Entamoeba histolytica as determined by polymerase chain reaction (PCR)-based DNA typing. The source of infection was most probably in Southern Italy where the family regularly spent their summer holidays. All three infected patients recovered after drug treatment. In a patient with a liver abscess or colitis, amoebiasis should be considered even in the absence of a history of a stay in the tropics. Stool samples should be examined for amoebic cysts and trophozoites. PCR analysis of parasite DNA extracted directly from stool samples makes differentiation between the morphologically identical cysts of E. histolytica and the non-pathogenic Entamoeba dispar possible. In addition, serum antibodies to E. histolytica are almost always present in symptomatic patients. Invasive infections with E. histolytica require treatment with a tissue amoebicidal drug, followed by a contact amoebicide to prevent recurrence. Currently, paromomycin is considered to be the first-line luminal amoebicide because of its efficacy and safety.
pubmed:commentsCorrections
pubmed:language
dut
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0028-2162
pubmed:author
pubmed:issnType
Print
pubmed:day
11
pubmed:volume
148
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1830-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
[Outbreak of amoebiasis in a Dutch family; tropics unexpectedly nearby].
pubmed:affiliation
Afd. Infectieziekten, Centrum voor Infectieziekten, Leids Universitair Medisch Centrum, Postbus 9600, 2300 RC Leiden.
pubmed:publicationType
Journal Article, English Abstract, Case Reports, Research Support, Non-U.S. Gov't