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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2004-10-20
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pubmed:abstractText |
The guanine to thymine polymorphism at position 894 of the eNOS gene (resulting in a change from glutamate to aspartate [Asp] at codon 298 [Asp298]) and the methylenetetrahydrofolate reductase (MTHFR) gene polymorphism (C677T) have been reported to be associated with atherosclerosis and cardiovascular disease. Endothelial dysfunction is considered to be the earliest stage of atherosclerosis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0828-282X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1229-34
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pubmed:dateRevised |
2008-4-9
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pubmed:meshHeading |
pubmed-meshheading:15494775-Adult,
pubmed-meshheading:15494775-Arteriosclerosis,
pubmed-meshheading:15494775-Base Sequence,
pubmed-meshheading:15494775-Coronary Artery Disease,
pubmed-meshheading:15494775-Endothelium, Vascular,
pubmed-meshheading:15494775-Genetic Predisposition to Disease,
pubmed-meshheading:15494775-Genotype,
pubmed-meshheading:15494775-Humans,
pubmed-meshheading:15494775-Japan,
pubmed-meshheading:15494775-Male,
pubmed-meshheading:15494775-Methylenetetrahydrofolate Reductase (NADPH2),
pubmed-meshheading:15494775-Molecular Sequence Data,
pubmed-meshheading:15494775-Nitric Oxide Synthase,
pubmed-meshheading:15494775-Nitric Oxide Synthase Type III,
pubmed-meshheading:15494775-Polymerase Chain Reaction,
pubmed-meshheading:15494775-Polymorphism, Genetic,
pubmed-meshheading:15494775-Probability,
pubmed-meshheading:15494775-Prospective Studies,
pubmed-meshheading:15494775-Reference Values
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pubmed:year |
2004
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pubmed:articleTitle |
Endothelial nitric oxide synthase and methylenetetrahydrofolate reductase gene polymorphisms are associated with endothelial dysfunction in young, healthy men.
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pubmed:affiliation |
Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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