rdf:type |
|
lifeskim:mentions |
umls-concept:C0013935,
umls-concept:C0016030,
umls-concept:C0021469,
umls-concept:C0023418,
umls-concept:C0033268,
umls-concept:C0043240,
umls-concept:C0078058,
umls-concept:C0302600,
umls-concept:C0331858,
umls-concept:C0332161,
umls-concept:C0917725,
umls-concept:C1171892,
umls-concept:C1704640,
umls-concept:C1706515
|
pubmed:issue |
1
|
pubmed:dateCreated |
2004-10-18
|
pubmed:abstractText |
The combined application of cytokines on embryonic fibroblasts and dermal substitute were studied for optimal skin defect coverage. The mechanism of combined treatment of leukemia inhibitory factor (LIF)-transfected embryonic fibroblasts and vascular endothelial growth factor (VEGF) were elucidated and subsequently the in vivo applications of both were tested in an artificial dermal substitute.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD34,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Complementary,
http://linkedlifedata.com/resource/pubmed/chemical/Fibronectins,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Leukemia Inhibitory Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Lif protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 3,
http://linkedlifedata.com/resource/pubmed/chemical/RNA,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0923-1811
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
36
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
11-23
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15488701-3T3 Cells,
pubmed-meshheading:15488701-Animals,
pubmed-meshheading:15488701-Antigens, CD34,
pubmed-meshheading:15488701-Blotting, Western,
pubmed-meshheading:15488701-Cell Proliferation,
pubmed-meshheading:15488701-Collagen,
pubmed-meshheading:15488701-DNA, Complementary,
pubmed-meshheading:15488701-Extracellular Matrix,
pubmed-meshheading:15488701-Fibroblasts,
pubmed-meshheading:15488701-Fibronectins,
pubmed-meshheading:15488701-Immunohistochemistry,
pubmed-meshheading:15488701-Interleukin-6,
pubmed-meshheading:15488701-Leukemia Inhibitory Factor,
pubmed-meshheading:15488701-MAP Kinase Signaling System,
pubmed-meshheading:15488701-Male,
pubmed-meshheading:15488701-Mice,
pubmed-meshheading:15488701-Mice, Inbred BALB C,
pubmed-meshheading:15488701-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:15488701-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:15488701-Neovascularization, Pathologic,
pubmed-meshheading:15488701-Phosphorylation,
pubmed-meshheading:15488701-RNA,
pubmed-meshheading:15488701-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15488701-Signal Transduction,
pubmed-meshheading:15488701-Skin,
pubmed-meshheading:15488701-Time Factors,
pubmed-meshheading:15488701-Transfection,
pubmed-meshheading:15488701-Vascular Endothelial Growth Factor A
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pubmed:year |
2004
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pubmed:articleTitle |
Leukemia inhibitory factor-transfected embryonic fibroblasts and vascular endothelial growth factor successfully improve the skin substitute wound healing by increasing angiogenesis and matrix production.
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pubmed:affiliation |
Division of Plastic and Reconstructive Surgery, Department of Developmental and Reconstructive Medicine, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto machi, Nagasaki 8528501, Japan. akitas@hf.rim.or.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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