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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2004-11-25
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pubmed:abstractText |
Ataxia-telangiectasia (A-T) is a neurologic disorder caused by mutations in the ataxia-telangiectasia mutated (ATM) gene. A clinical diagnosis of A-T is confirmed by radiosensitivity testing and immunoblotting for ATM protein. Because both of these tests have long turnaround times (> or =3 months), we developed a rapid immunoassay to measure ATM protein and determined its sensitivity and specificity for diagnosing A-T.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0009-9147
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2302-8
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pubmed:dateRevised |
2011-11-2
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pubmed:meshHeading |
pubmed-meshheading:15486025-Ataxia Telangiectasia,
pubmed-meshheading:15486025-Cell Cycle Proteins,
pubmed-meshheading:15486025-DNA-Binding Proteins,
pubmed-meshheading:15486025-Humans,
pubmed-meshheading:15486025-Immunoblotting,
pubmed-meshheading:15486025-Immunoenzyme Techniques,
pubmed-meshheading:15486025-Leukocytes, Mononuclear,
pubmed-meshheading:15486025-Protein-Serine-Threonine Kinases,
pubmed-meshheading:15486025-Recombinant Proteins,
pubmed-meshheading:15486025-Sensitivity and Specificity,
pubmed-meshheading:15486025-Tumor Suppressor Proteins,
pubmed-meshheading:15486025-Vaccinia virus
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pubmed:year |
2004
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pubmed:articleTitle |
Immunoassay to measure ataxia-telangiectasia mutated protein in cellular lysates.
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pubmed:affiliation |
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095, USA. abutch@mednet.ucla.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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