Source:http://linkedlifedata.com/resource/pubmed/id/15485011
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2004-10-15
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pubmed:abstractText |
The INNO-LIA ANA Update is a qualitative multiparameter line immunoassay for detection of autoantibodies to several different antigens associated with connective tissue disorders. We sought to optimize and validate the cut-off values for its antigen-specific components: SmB, SmD, RNP-70k, RNP-A, RNP-C, SSA/Ro52, SSA/Ro60, SSB/La, Cenp-B, Topo-I, Jo-1, ribosomal P, and histones. Our aim was to achieve 98% specificity for each of the markers, with respect to differential disease controls, while maintaining sensitivity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0392-856X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
579-88
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15485011-Antigens,
pubmed-meshheading:15485011-Autoantibodies,
pubmed-meshheading:15485011-Biological Markers,
pubmed-meshheading:15485011-Connective Tissue Diseases,
pubmed-meshheading:15485011-Humans,
pubmed-meshheading:15485011-Immunoassay,
pubmed-meshheading:15485011-Reference Values,
pubmed-meshheading:15485011-Sensitivity and Specificity
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pubmed:articleTitle |
Clinical optimization and multicenter validation of antigen-specific cut-off values on the INNO-LIA ANA update for the detection of autoantibodies in connective tissue disorders.
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pubmed:affiliation |
Innogenetics NV, Gent, Belgium.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Validation Studies
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