Linked Life Data

15482934

Source:http://linkedlifedata.com/resource/pubmed/id/15482934

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
22
pubmed:dateCreated
2004-10-14
pubmed:abstractText
This work presents a study QSAR among the MAO A inhibitory activity (IMAO A) of a xanthones series correlated with descriptors like the E-state index (S(i)), molecular connectivity (chi) and shape (k) descriptors. The xanthones group (9-H-xanton-9-onas) are of natural or synthetic origin, they present eight positions for the substitution and their MAO A inhibitory activity is reported in the work from Gnerre et al. The descriptors included in the adjusted model were selected to describe the molecular structure of the compounds. The model was selected using the leave-one-out method, the cross-validation statistics indicate a model useful for prediction: r(2)=0.847 and s=8.069, calculated by multiple linear regression.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0960-894X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5611-7
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
QSAR modeling of the MAO inhibitory activity of xanthones derivatives.
pubmed:affiliation
Facultad de Agroindustrias, UNNE, Cdte. Fernández 755, Sáenz Peña 3700, Chaco, Argentina. nora@fai.unne.edu.ar
pubmed:publicationType
Journal Article