Linked Life Data

1548227

Source:http://linkedlifedata.com/resource/pubmed/id/1548227

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1992-4-23
pubmed:abstractText
Serrawettin W2, a surface-active exolipid produced by nonpigmented Serratia marcescens NS 25, was examined for its chemical structure and physiological functions. The chemical structure was determined by degradation analyses, infrared spectroscopy, mass spectrometry, and proton magnetic resonance spectroscopy. Serrawettin W2 was shown to be a novel cyclodepsipeptide containing a fatty acid (3-hydroxydecanoic acid) and five amino acids. The peptide was proposed to be D-leucine (N-bonded to the carboxylate of the fatty acid)-L-serine-L-threonine-D-phenylalanine-L-isoleucine (bonded to the 3-hydroxyl group). By examining the effects of isolated serrawettin W2 on serrawettinless mutants, this lipopeptide was shown to be active in the promotion of flagellum-independent spreading growth of the bacteria on a hard agar surface. The parent strain NS 25 formed a giant colony with a self-similar characteristic after incubation for a relatively long time (1 to 2 weeks), similar to other fractal colony-producing strains of S. marcescens (producers of the different serrawettins W1 and W3). On a semisolid medium that permitted flagellum-dependent spreading growth, an external supply of serrawettin W2 accelerated surface translocation of a serrawettinless mutant during a short period (12 h) of observation. In contrast, bacterial translocation in the subsurface space of the semisolid agar was not enhanced by serrawettins. Thus, the extracellular lipids seem to contribute specifically to the surface translocation of the bacteria by exhibiting surfactant activity.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/1548227-13278318, http://linkedlifedata.com/resource/pubmed/commentcorrection/1548227-16345840, http://linkedlifedata.com/resource/pubmed/commentcorrection/1548227-16347347, http://linkedlifedata.com/resource/pubmed/commentcorrection/1548227-16347926, http://linkedlifedata.com/resource/pubmed/commentcorrection/1548227-1648079, http://linkedlifedata.com/resource/pubmed/commentcorrection/1548227-2345132, http://linkedlifedata.com/resource/pubmed/commentcorrection/1548227-2507521, http://linkedlifedata.com/resource/pubmed/commentcorrection/1548227-2693193, http://linkedlifedata.com/resource/pubmed/commentcorrection/1548227-2848009, http://linkedlifedata.com/resource/pubmed/commentcorrection/1548227-3045093, http://linkedlifedata.com/resource/pubmed/commentcorrection/1548227-4334639, http://linkedlifedata.com/resource/pubmed/commentcorrection/1548227-4559685, http://linkedlifedata.com/resource/pubmed/commentcorrection/1548227-7201782
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0021-9193
pubmed:author
pubmed:issnType
Print
pubmed:volume
174
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1769-76
pubmed:dateRevised
2010-9-7
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
A novel extracellular cyclic lipopeptide which promotes flagellum-dependent and -independent spreading growth of Serratia marcescens.
pubmed:affiliation
Department of Bacteriology, Niigata University School of Medicine, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't