Linked Life Data

15480771

Source:http://linkedlifedata.com/resource/pubmed/id/15480771

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2004-10-13
pubmed:abstractText
A Japanese male patient developed bilateral retinoblastomas at the age of 1 year, but remained continuously disease-free after enucleation of the left eye and radiation therapy to the right eye. He noticed a painless hard mass around the right temporal bone when he was 25 years old. Biopsy specimen showed a small multi-nodular proliferation of tumor cells with prominent rosette-like structures. Eosinophilic material with focal mineralization was seen in the center of the rosettes. Immunostaining of the tumor cells showed positive reactions for epithelial membrane antigens CD 56 and CD 99. The patient was treated with systemic chemotherapy, and the tumor partially diminished. It is well known that a few osteosarcomas show a rosette-like appearance with production of osteoid in the center, but this is the first case of second primary osteosarcoma with prominent rosette-like features.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0945-6317
pubmed:author
pubmed:issnType
Print
pubmed:volume
445
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
421-4
pubmed:dateRevised
2010-9-1
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Second primary osteosarcoma with rosette-like structure in a patient with retinoblastoma.
pubmed:affiliation
Department of Orthopedic Surgery, Akita University School of Medicine, Hondo 1-1-1, Akita 010-8543 Akita, Japan. cshokada@med.akita-u.ac.jp
pubmed:publicationType
Journal Article, Case Reports