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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1992-4-23
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pubmed:abstractText |
The inflammatory activity in 108 bowel segments of 40 patients with suspected or known inflammatory bowel disease was assessed macroscopically by endoscopy, histology and technetium-99m hexamethyl propylene amine oxine (99mTc-HMPAO) leucocytes using a numerical grading system (scores 0-3). A 4-h series of scintigrams showed a significant correlation with both histological and macroscopical assessment of disease activity (rho = 0.850, P less than 0.001 and rho = 0.773, P less than 0.001, respectively). Sensitivity, specificity and accuracy of scintigraphy in detecting active inflammatory segments were 85%, 92% and 89%, respectively. A normal scintigram did not completely exclude mild inflammatory activity, especially in the rectosigmoid area. 99mTc-HMPAO leucocytes offer an accurate and non-invasive alternative for the assessment of disease activity in ulcerative colitis and Crohn's disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0340-6997
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
14-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1547802-Adult,
pubmed-meshheading:1547802-Aged,
pubmed-meshheading:1547802-Colitis, Ulcerative,
pubmed-meshheading:1547802-Crohn Disease,
pubmed-meshheading:1547802-Female,
pubmed-meshheading:1547802-Finland,
pubmed-meshheading:1547802-Humans,
pubmed-meshheading:1547802-Inflammatory Bowel Diseases,
pubmed-meshheading:1547802-Leukocytes,
pubmed-meshheading:1547802-Male,
pubmed-meshheading:1547802-Middle Aged,
pubmed-meshheading:1547802-Organotechnetium Compounds,
pubmed-meshheading:1547802-Oximes,
pubmed-meshheading:1547802-Prospective Studies,
pubmed-meshheading:1547802-Technetium Tc 99m Exametazime
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pubmed:year |
1992
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pubmed:articleTitle |
Technetium-99m hexamethyl propylene amine oxine leucocytes in the assessment of disease activity in inflammatory bowel disease.
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pubmed:affiliation |
Department of Radiology, Päijät-Häme Central Hospital, Lahti, Finland.
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pubmed:publicationType |
Journal Article
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