| pubmed-article:15476240 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15476240 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:15476240 | lifeskim:mentions | umls-concept:C0024141 | lld:lifeskim |
| pubmed-article:15476240 | lifeskim:mentions | umls-concept:C0262950 | lld:lifeskim |
| pubmed-article:15476240 | lifeskim:mentions | umls-concept:C0011306 | lld:lifeskim |
| pubmed-article:15476240 | lifeskim:mentions | umls-concept:C0282580 | lld:lifeskim |
| pubmed-article:15476240 | lifeskim:mentions | umls-concept:C0205396 | lld:lifeskim |
| pubmed-article:15476240 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:15476240 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:15476240 | pubmed:dateCreated | 2004-10-18 | lld:pubmed |
| pubmed-article:15476240 | pubmed:abstractText | Systemic lupus erythematosus (SLE) is characterized by the existence of a heterogeneous group of autoantibodies directed against intact nuclear structures, such as nucleosomes. The most prominent of these autoantibodies are those directed against double-stranded DNA (dsDNA) and histones. The majority are of the IgG isotype and show affinity maturation, both of which are known hallmarks of T cell help. Much evidence suggests that the nucleosome is a major candidate autoantigen in SLE. In this study, a novel strategy was used to identify the critical CD4+ T cell autoepitopes in nucleosomes. In addition, peptide-based therapy was then performed in a lupus animal model. | lld:pubmed |
| pubmed-article:15476240 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15476240 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15476240 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:15476240 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15476240 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15476240 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15476240 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15476240 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15476240 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15476240 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:15476240 | pubmed:issn | 0004-3591 | lld:pubmed |
| pubmed-article:15476240 | pubmed:author | pubmed-author:ChiangBor-Lue... | lld:pubmed |
| pubmed-article:15476240 | pubmed:author | pubmed-author:YauPeter MPM | lld:pubmed |
| pubmed-article:15476240 | pubmed:author | pubmed-author:SuenJau-LingJ... | lld:pubmed |
| pubmed-article:15476240 | pubmed:author | pubmed-author:ChuangYa-HuiY... | lld:pubmed |
| pubmed-article:15476240 | pubmed:author | pubmed-author:TsaiBor-YuBY | lld:pubmed |
| pubmed-article:15476240 | pubmed:copyrightInfo | Copyright 2004 American College of Rheumatology | lld:pubmed |
| pubmed-article:15476240 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15476240 | pubmed:volume | 50 | lld:pubmed |
| pubmed-article:15476240 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15476240 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15476240 | pubmed:pagination | 3250-9 | lld:pubmed |
| pubmed-article:15476240 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:meshHeading | pubmed-meshheading:15476240... | lld:pubmed |
| pubmed-article:15476240 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15476240 | pubmed:articleTitle | Treatment of murine lupus using nucleosomal T cell epitopes identified by bone marrow-derived dendritic cells. | lld:pubmed |
| pubmed-article:15476240 | pubmed:affiliation | Kaoshiung Medical University, Kaoshiung, Taiwan, Republic of China. | lld:pubmed |
| pubmed-article:15476240 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15476240 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15476240 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15476240 | lld:pubmed |
