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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2004-10-7
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pubmed:abstractText |
Sulfamethoxazole hydroxylamine formation, in combination with long-term oxidative stress, is thought to be the cause of high rates of adverse drug reactions to sulfamethoxazole in human immunodeficiency virus (HIV)-infected subjects. Therefore the goal of this study was to determine the effect of fluconazole, clarithromycin, and rifabutin on sulfamethoxazole hydroxylamine formation in individuals with HIV-1 infection.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0009-9236
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
313-22
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15470330-Adult,
pubmed-meshheading:15470330-Anti-Infective Agents,
pubmed-meshheading:15470330-Area Under Curve,
pubmed-meshheading:15470330-CD4 Lymphocyte Count,
pubmed-meshheading:15470330-Clarithromycin,
pubmed-meshheading:15470330-Drug Interactions,
pubmed-meshheading:15470330-Female,
pubmed-meshheading:15470330-Fluconazole,
pubmed-meshheading:15470330-HIV Infections,
pubmed-meshheading:15470330-HIV-1,
pubmed-meshheading:15470330-Humans,
pubmed-meshheading:15470330-Male,
pubmed-meshheading:15470330-Middle Aged,
pubmed-meshheading:15470330-Rifabutin,
pubmed-meshheading:15470330-Sulfamethoxazole,
pubmed-meshheading:15470330-Trimethoprim-Sulfamethoxazole Combination
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pubmed:year |
2004
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pubmed:articleTitle |
The effect of clarithromycin, fluconazole, and rifabutin on sulfamethoxazole hydroxylamine formation in individuals with human immunodeficiency virus infection (AACTG 283).
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pubmed:affiliation |
University of Washington, Seattle 98195, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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