Linked Life Data

1546927

Source:http://linkedlifedata.com/resource/pubmed/id/1546927

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1992-4-15
pubmed:abstractText
In four patients, ulcerative disease of the colon developed while they were taking nonsteroidal anti-inflammatory drugs (NSAIDs). Clinical presentation and laboratory and colonoscopic findings were similar to those of inflammatory bowel disease. Review of the literature disclosed 74 additional cases of NSAID-induced colitis in adults. This is a rare but serious, sometimes fatal, complication of NSAID therapy. The elderly and those taking long-term NSAID therapy appear to be at highest risk. The pathogenesis is thought to be related to inhibition of intestinal prostaglandin synthesis. Whether some NSAIDs are more likely to induce colitis than others is not known. Since NSAIDs are so widely prescribed and some are available without a prescription, heightened awareness by physicians and the lay public will be important in reducing injury from this disease, both by prevention and earlier recognition.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0003-9926
pubmed:author
pubmed:issnType
Print
pubmed:volume
152
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
625-32
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Colitis induced by nonsteroidal anti-inflammatory drugs. Report of four cases and review of the literature.
pubmed:affiliation
Department of Medicine, Trumbull Memorial Hospital, Warren, Ohio.
pubmed:publicationType
Journal Article, Review, Case Reports