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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-4-13
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pubmed:abstractText |
Three methods to detect Chlamydia trachomatis in endocervical swab specimens collected from 502 women with genitourinary or abdominopelvic symptoms were evaluated: (1) a direct immunofluorescence assay, (2) an enzyme-linked immunoabsorbent assay, confirming positive samples with a blocking assay, and (3) conventional tissue cell culture. C. trachomatis was detected by at least one method in 72 specimens, of which 56 (11%) were determined to be true-positive results by repeated testing and by performing a confirmatory assay. The sensitivity, specificity, and positive and negative predictive values were 91%, 100%, 100%, and 99%, respectively, for culture and the enzyme-linked immunoabsorbent assay plus blocking assay and 74%, 98%, 83%, and 96%, respectively, for the direct immunofluorescence assay. In this population of women, using the enzyme-linked immunoabsorbent assay with the confirmatory assay is a rapid, reliable, and cost-effective alternative to culture for diagnosing infection with C. trachomatis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0002-9173
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
209-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1546689-Adult,
pubmed-meshheading:1546689-Antibodies, Viral,
pubmed-meshheading:1546689-Cervix Uteri,
pubmed-meshheading:1546689-Chlamydia trachomatis,
pubmed-meshheading:1546689-False Positive Reactions,
pubmed-meshheading:1546689-Female,
pubmed-meshheading:1546689-Fluorescent Antibody Technique,
pubmed-meshheading:1546689-Humans,
pubmed-meshheading:1546689-Immunoenzyme Techniques,
pubmed-meshheading:1546689-Lipopolysaccharides,
pubmed-meshheading:1546689-Sensitivity and Specificity,
pubmed-meshheading:1546689-Vaginal Smears
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pubmed:year |
1992
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pubmed:articleTitle |
Chlamydiazyme plus blocking assay to detect Chlamydia trachomatis in endocervical specimens.
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pubmed:affiliation |
Department of Pathology, University of Nebraska Medical Center, Omaha 68198-3135.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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