Source:http://linkedlifedata.com/resource/pubmed/id/15464654
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
2004-10-6
|
pubmed:abstractText |
Hereditary hemochromatosis comprises several inherited disorders of iron homeostasis characterized by increased gastrointestinal iron absorpstion and resultant tissue iron deposition. The identification of HFE and other genes involved in iron metabolism has greatly expanded our understanding of hereditary hemochromatosis. Two major hypotheses have been proposed to explain the pathogenesis of HFE-related hereditary hemochromatosis: the hepcidin hypothesis and the duodenal crypt cell programming hypothesis.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
1089-3261
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
755-73, vii
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:15464654-Animals,
pubmed-meshheading:15464654-Antimicrobial Cationic Peptides,
pubmed-meshheading:15464654-Disease Models, Animal,
pubmed-meshheading:15464654-Duodenum,
pubmed-meshheading:15464654-Genetic Predisposition to Disease,
pubmed-meshheading:15464654-Hemochromatosis,
pubmed-meshheading:15464654-Humans,
pubmed-meshheading:15464654-Iron,
pubmed-meshheading:15464654-Mice
|
pubmed:year |
2004
|
pubmed:articleTitle |
Pathogenesis of hereditary hemochromatosis.
|
pubmed:affiliation |
Department of Pediatrics, Saint Louis University School of Medicine, Cardinal Glennon Childrens Hospital, 1465 S. Grand Blvd, St. Louis, MO 63104, USA. flemingr@slu.edu
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review
|