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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2004-10-6
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pubmed:abstractText |
Aim of the study was to get a deeper insight in the mechanisms regulating avascularity of cartilaginious tissues. In the center of our interest was the expression of the anti-angiogenic fragment of collagen XVIII and its potency to inhibit angiogenesis. We observed a strong endostatin/collagen XVIII production in articular and fibrocartilage and an inhibitory potency concerning the VEGF-signalling pathway.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0945-053X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
267-76
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15464359-Aging,
pubmed-meshheading:15464359-Angiogenesis Inhibitors,
pubmed-meshheading:15464359-Animals,
pubmed-meshheading:15464359-Cartilage,
pubmed-meshheading:15464359-Cartilage, Articular,
pubmed-meshheading:15464359-Cells, Cultured,
pubmed-meshheading:15464359-Chondrocytes,
pubmed-meshheading:15464359-Collagen Type XVIII,
pubmed-meshheading:15464359-Endostatins,
pubmed-meshheading:15464359-Extracellular Signal-Regulated MAP Kinases,
pubmed-meshheading:15464359-Fetus,
pubmed-meshheading:15464359-Humans,
pubmed-meshheading:15464359-Menisci, Tibial,
pubmed-meshheading:15464359-Nitric Oxide,
pubmed-meshheading:15464359-Osmolar Concentration,
pubmed-meshheading:15464359-Phosphorylation,
pubmed-meshheading:15464359-RNA, Messenger,
pubmed-meshheading:15464359-Rats,
pubmed-meshheading:15464359-Rats, Wistar,
pubmed-meshheading:15464359-Vascular Endothelial Growth Factor A
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pubmed:year |
2004
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pubmed:articleTitle |
Endostatin/collagen XVIII--an inhibitor of angiogenesis--is expressed in cartilage and fibrocartilage.
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pubmed:affiliation |
Department of Anatomy, Christian-Albrechts-University, Olshausenstrasse 40, D-24098 Kiel, Germany. t.pufe@anat.uni-kiel.de
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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