Source:http://linkedlifedata.com/resource/pubmed/id/15459346
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5700
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pubmed:dateCreated |
2004-11-19
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pubmed:databankReference | |
pubmed:abstractText |
Microbial sensory rhodopsins are a family of membrane-embedded photoreceptors in prokaryotic and eukaryotic organisms. Structures of archaeal rhodopsins, which function as light-driven ion pumps or photosensors, have been reported. We present the structure of a eubacterial rhodopsin, which differs from those of previously characterized archaeal rhodopsins in its chromophore and cytoplasmic-side portions. Anabaena sensory rhodopsin exhibits light-induced interconversion between stable 13-cis and all-trans states of the retinylidene protein. The ratio of its cis and trans chromophore forms depends on the wavelength of illumination, thus providing a mechanism for a single protein to signal the color of light, for example, to regulate color-sensitive processes such as chromatic adaptation in photosynthesis. Its cytoplasmic half channel, highly hydrophobic in the archaeal rhodopsins, contains numerous hydrophilic residues networked by water molecules, providing a connection from the photoactive site to the cytoplasmic surface believed to interact with the receptor's soluble 14-kilodalton transducer.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Archaeal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Lipid Bilayers,
http://linkedlifedata.com/resource/pubmed/chemical/Sensory Rhodopsins,
http://linkedlifedata.com/resource/pubmed/chemical/Water
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1095-9203
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
19
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pubmed:volume |
306
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1390-3
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15459346-Anabaena,
pubmed-meshheading:15459346-Archaeal Proteins,
pubmed-meshheading:15459346-Bacterial Proteins,
pubmed-meshheading:15459346-Binding Sites,
pubmed-meshheading:15459346-Chemistry, Physical,
pubmed-meshheading:15459346-Crystallography, X-Ray,
pubmed-meshheading:15459346-Cytoplasm,
pubmed-meshheading:15459346-Hydrogen Bonding,
pubmed-meshheading:15459346-Light,
pubmed-meshheading:15459346-Lipid Bilayers,
pubmed-meshheading:15459346-Models, Molecular,
pubmed-meshheading:15459346-Physicochemical Phenomena,
pubmed-meshheading:15459346-Protein Conformation,
pubmed-meshheading:15459346-Protein Structure, Secondary,
pubmed-meshheading:15459346-Sensory Rhodopsins,
pubmed-meshheading:15459346-Water
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pubmed:year |
2004
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pubmed:articleTitle |
Anabaena sensory rhodopsin: a photochromic color sensor at 2.0 A.
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pubmed:affiliation |
Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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