|
pubmed:abstractText |
MicroRNAs are approximately 17-24 nt. noncoding RNAs found in all eukaryotes that degrade messenger RNAs via RNA interference (if they bind in a perfect or near-perfect complementarity to the target mRNA), or arrest translation (if the binding is imperfect). Several microRNA targets have been identified in lower organisms, but only one mammalian microRNA target has yet been validated experimentally.
|
|
pubmed:affiliation |
University of Illinois at Chicago, UIC Psychiatric Institute, MC 912, 1601 W, Taylor Street, room 285 Chicago, IL 60612, USA. smalheiser@psych.uic.edu
|
