Source:http://linkedlifedata.com/resource/pubmed/id/15451898
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
2004-9-28
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| pubmed:abstractText |
Gastroparesis is a disorder of delayed gastric emptying that is often chronic in nature. Up to 50% of type 1 diabetic subjects have symptoms of gastroparesis, which include nausea, vomiting, and early satiety. Elevated pyloric pressures may be responsible for delayed gastric emptying in diabetic subjects. Botulinum toxin inhibits the release of acetylcholine and produces transient paralysis when injected into smooth muscle. The aim of this study was to determine whether injection of the pylorus with botulinum toxin in patients with diabetic gastroparesis improves symptoms of gastroparesis, alters gastric emptying scan time, and/or changes weight and insulin use.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0149-5992
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| pubmed:author | |
| pubmed:copyrightInfo |
Copyright 2004 American Diabetes Association
|
| pubmed:issnType |
Print
|
| pubmed:volume |
27
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
2341-7
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| pubmed:dateRevised |
2010-11-18
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| pubmed:meshHeading |
pubmed-meshheading:15451898-Adult,
pubmed-meshheading:15451898-Botulinum Toxins, Type A,
pubmed-meshheading:15451898-Diabetes Mellitus, Type 1,
pubmed-meshheading:15451898-Female,
pubmed-meshheading:15451898-Follow-Up Studies,
pubmed-meshheading:15451898-Gastric Emptying,
pubmed-meshheading:15451898-Gastroparesis,
pubmed-meshheading:15451898-Gastroscopy,
pubmed-meshheading:15451898-Humans,
pubmed-meshheading:15451898-Injections, Intralesional,
pubmed-meshheading:15451898-Male,
pubmed-meshheading:15451898-Manometry,
pubmed-meshheading:15451898-Middle Aged,
pubmed-meshheading:15451898-Probability,
pubmed-meshheading:15451898-Pylorus,
pubmed-meshheading:15451898-Reference Values,
pubmed-meshheading:15451898-Risk Assessment,
pubmed-meshheading:15451898-Severity of Illness Index,
pubmed-meshheading:15451898-Single-Blind Method,
pubmed-meshheading:15451898-Treatment Outcome
|
| pubmed:year |
2004
|
| pubmed:articleTitle |
The treatment of diabetic gastroparesis with botulinum toxin injection of the pylorus.
|
| pubmed:affiliation |
Marvin M. Schuster Center for Digestive and Motility Disorders, Johns Hopkins University, School of Medicine, Baltimore, MD, USA. brian.lacy@hitchcock.org
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| pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't
|