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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2004-9-27
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pubmed:abstractText |
Folate deficiency is considered to increase the risk of developing esophageal cancer. Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme involved in folate metabolism. A single C --> T substitution at nucleotide 677 of the MTHFR cDNA influences enzyme activity. The purpose of this study is to compare the association of the MTHFR C677T polymorphism with susceptibility to esophageal squamous cell carcinoma (ESCC).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0171-5216
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pubmed:author |
pubmed-author:ChenZhifengZ,
pubmed-author:GabbertHelmut EHE,
pubmed-author:KielSybilleS,
pubmed-author:LiYanY,
pubmed-author:SarbiaMarioM,
pubmed-author:SchulzWolfgang AWA,
pubmed-author:WangRuiR,
pubmed-author:WangShijieS,
pubmed-author:WenDengguiD,
pubmed-author:ZhangJianhuiJ,
pubmed-author:ZhangLiweiL,
pubmed-author:ZotzRainer BRB
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pubmed:issnType |
Print
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pubmed:volume |
130
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
574-80
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15449187-Asian Continental Ancestry Group,
pubmed-meshheading:15449187-Carcinoma, Squamous Cell,
pubmed-meshheading:15449187-Case-Control Studies,
pubmed-meshheading:15449187-China,
pubmed-meshheading:15449187-Esophageal Neoplasms,
pubmed-meshheading:15449187-European Continental Ancestry Group,
pubmed-meshheading:15449187-Genetic Predisposition to Disease,
pubmed-meshheading:15449187-Genotype,
pubmed-meshheading:15449187-Germany,
pubmed-meshheading:15449187-Humans,
pubmed-meshheading:15449187-Methylenetetrahydrofolate Reductase (NADPH2),
pubmed-meshheading:15449187-Polymorphism, Genetic,
pubmed-meshheading:15449187-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2004
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pubmed:articleTitle |
Methylenetetrahydrofolate reductase C677T polymorphism and predisposition towards esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population.
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pubmed:affiliation |
Institute of Pathology, University of Düsseldorf, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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