pubmed:abstractText |
Major problems in the management of keratomycosis stem from the difficulty of its diagnosis and limited choice of antifungal agents. In the present paper we propose a new method of detecting (1,3)-beta-D-glucan, one of the major components of fungal cell wall, in tears from an animal model of keratomycosis. In addition, we investigated the efficacy of topical application of micafungin, a new antifungal agent that inhibits the activity of (1,3)-beta-D-glucan synthase in this animal model.
|
pubmed:affiliation |
Department of Ophthalmology, University of Tsukuba Institute of Clinical Medicine, Tennoudai 1-1-1, Tsukuba, Ibaraki 305-8565, Japan. sanken-tky@umin.ac.jp
|