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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1992-4-9
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pubmed:abstractText |
The relation between the maximal velocity of red blood cell sodium-lithium countertransport and blood pressure/hypertension has been studied in 2,748 men and women aged 25-74 years who participated in the 1983-85 baseline examination of the Gubbio Population Study, an epidemiologic investigation performed in a hill town of north central Italy. Men had a higher sodium-lithium countertransport velocity than women at all ages, and, in both sexes, a higher velocity was observed at successive ages. Hypertensives of both sexes had a higher sodium-lithium countertransport velocity than normotensive individuals, the difference remaining significant after control for age, body mass index and plasma uric acid concentration. Individuals with high sodium-lithium countertransport velocity had significantly greater prevalence of hypertension in both sexes. The data show the existence of a cross-sectional association between sodium-lithium countertransport velocity and hypertension in general population. Prospective study of the Gubbio population is now in progress to investigate the relation between baseline sodium-lithium countertransport velocity, its change over the years and the incidence of hypertension.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0730-0077
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
261-9
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pubmed:dateRevised |
2008-2-12
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pubmed:meshHeading |
pubmed-meshheading:1541040-Adult,
pubmed-meshheading:1541040-Aged,
pubmed-meshheading:1541040-Biological Transport, Active,
pubmed-meshheading:1541040-Blood Pressure,
pubmed-meshheading:1541040-Cross-Sectional Studies,
pubmed-meshheading:1541040-Erythrocytes,
pubmed-meshheading:1541040-Female,
pubmed-meshheading:1541040-Humans,
pubmed-meshheading:1541040-Hypertension,
pubmed-meshheading:1541040-Italy,
pubmed-meshheading:1541040-Kinetics,
pubmed-meshheading:1541040-Lithium,
pubmed-meshheading:1541040-Male,
pubmed-meshheading:1541040-Middle Aged,
pubmed-meshheading:1541040-Sodium
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pubmed:year |
1992
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pubmed:articleTitle |
The Gubbio data. Epidemiology and pathophysiology. Gubbio Study Research Group.
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pubmed:affiliation |
Merck Sharp & Dohme, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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