rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1992-3-27
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pubmed:databankReference |
|
pubmed:abstractText |
Differential hybridization analysis was used to identify molecular differences between a relative benign and a highly aggressive rat prostatic tumor derived from the Dunning R-3327-H adenocarcinoma. From the several differentially expressed mRNAs identified, we here report the characterization of pBUS51 which encodes a transcript highly expressed in all-anaplastic Dunning tumors. Only a very low expression was detectable in normal rat prostate or in the differentiated tumors of the Dunning system. Nucleotide sequence analysis and computer-assisted database comparison revealed that pBUS51 was highly homologous to vimentin and therefore likely the rat homolog of this protein.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0006-291X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
14
|
pubmed:volume |
182
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1254-9
|
pubmed:dateRevised |
2006-5-1
|
pubmed:meshHeading |
pubmed-meshheading:1540169-Amino Acid Sequence,
pubmed-meshheading:1540169-Animals,
pubmed-meshheading:1540169-Base Sequence,
pubmed-meshheading:1540169-Blotting, Northern,
pubmed-meshheading:1540169-Cell Line,
pubmed-meshheading:1540169-DNA, Neoplasm,
pubmed-meshheading:1540169-Gene Library,
pubmed-meshheading:1540169-Humans,
pubmed-meshheading:1540169-Male,
pubmed-meshheading:1540169-Molecular Sequence Data,
pubmed-meshheading:1540169-Nucleic Acid Hybridization,
pubmed-meshheading:1540169-Plasmids,
pubmed-meshheading:1540169-Prostatic Neoplasms,
pubmed-meshheading:1540169-RNA, Neoplasm,
pubmed-meshheading:1540169-Rats,
pubmed-meshheading:1540169-Restriction Mapping,
pubmed-meshheading:1540169-Vimentin
|
pubmed:year |
1992
|
pubmed:articleTitle |
Differential expression of vimentin in rat prostatic tumors.
|
pubmed:affiliation |
Department of Urology, Urological Research Laboratory, University of Nijmegen, The Netherlands.
|
pubmed:publicationType |
Journal Article
|