Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2004-10-6
pubmed:abstractText
The objective of this study was to evaluate the safety and efficacy of cutting balloon angioplasty (CBA) for the treatment of in-stent restenosis prior to intracoronary brachytherapy (ICB). Cutting balloon angioplasty may reduce the incidence of uncontrolled dissection requiring adjunctive stenting and may limit "melon seeding" and geographic miss in patients with in-stent restenosis who are subsequently treated with ICB. We performed a retrospective case-control analysis of 134 consecutive patients with in-stent restenosis who were treated with ICB preceded by either CBA or conventional balloon angioplasty. We identified 44 patients who underwent CBA and ICB, and 90 control patients who underwent conventional percutaneous transluminal coronary angioplasty (PTCA) and ICB for the treatment of in-stent restenosis. Adjunctive coronary stenting was performed in 13 patients (29.5%) in the CBA/ICB group and 41 patients (45.6%; P < 0.001) in the PTCA/ICB group. There was no difference in the injury length or active treatment (ICB) length. The procedural and angiographic success rates were similar in both groups. There were no statistically significant differences in the incidence of death, myocardial infarction, recurrent angina pectoris, subsequent target lumen revascularization, or the composite endpoint of all four clinical outcomes (P > 0.05). Despite sound theoretical reasons why CBA may be better than conventional balloon angioplasty for treatment of in-stent restenosis with ICB, and despite a reduction in the need for adjunctive coronary stenting, we were unable to identify differences in clinical outcome.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1522-1946
pubmed:author
pubmed:copyrightInfo
(c) 2004 Wiley-Liss, Inc.
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
152-7
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:15390249-Aged, pubmed-meshheading:15390249-Angioplasty, Balloon, pubmed-meshheading:15390249-Angioplasty, Balloon, Coronary, pubmed-meshheading:15390249-Brachytherapy, pubmed-meshheading:15390249-Case-Control Studies, pubmed-meshheading:15390249-Chi-Square Distribution, pubmed-meshheading:15390249-Combined Modality Therapy, pubmed-meshheading:15390249-Coronary Angiography, pubmed-meshheading:15390249-Coronary Restenosis, pubmed-meshheading:15390249-Female, pubmed-meshheading:15390249-Humans, pubmed-meshheading:15390249-Male, pubmed-meshheading:15390249-Middle Aged, pubmed-meshheading:15390249-Registries, pubmed-meshheading:15390249-Retrospective Studies, pubmed-meshheading:15390249-Statistics, Nonparametric, pubmed-meshheading:15390249-Stents, pubmed-meshheading:15390249-Treatment Outcome
pubmed:year
2004
pubmed:articleTitle
Cutting balloon angioplasty vs. conventional balloon angioplasty in patients receiving intracoronary brachytherapy for the treatment of in-stent restenosis.
pubmed:affiliation
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA. pfasseas@mcw.edu
pubmed:publicationType
Journal Article, Comparative Study