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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2004-9-23
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pubmed:abstractText |
Statins are known to enhance atherosclerotic plaque stability through influences on extracellular matrix homeostasis. Net matrix production reflects the relative balance of matrix production and degradation through enzymes such as matrix metalloproteinases (MMPs) and their inhibitors, tissue inhibitor of MMP (TIMPs). The effects of statins on endothelial cell production of these parameters following co-exposure with a proatherogenic stimulus such as high glucose are not known.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0742-3071
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1102-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15384957-Blotting, Western,
pubmed-meshheading:15384957-Cells, Cultured,
pubmed-meshheading:15384957-Collagen Type IV,
pubmed-meshheading:15384957-Dose-Response Relationship, Drug,
pubmed-meshheading:15384957-Endothelial Cells,
pubmed-meshheading:15384957-Extracellular Matrix,
pubmed-meshheading:15384957-Glucose,
pubmed-meshheading:15384957-Heptanoic Acids,
pubmed-meshheading:15384957-Humans,
pubmed-meshheading:15384957-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:15384957-Matrix Metalloproteinase 2,
pubmed-meshheading:15384957-Pyrroles,
pubmed-meshheading:15384957-Tissue Inhibitor of Metalloproteinase-1,
pubmed-meshheading:15384957-Tissue Inhibitor of Metalloproteinase-2,
pubmed-meshheading:15384957-Umbilical Veins
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pubmed:year |
2004
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pubmed:articleTitle |
The effects of high glucose and atorvastatin on endothelial cell matrix production.
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pubmed:affiliation |
Renal Research Group, Kolling Institute, Royal North Shore Hospital, University of Sydney, NSW, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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