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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2004-9-22
pubmed:abstractText
The pressure pulse is amplified between the aorta and peripheral sites. This study compares two methods to estimate pressure pulse amplification (PPA) between the aorta and the brachial artery. Method 1: PPA was determined from a multi-parameter linear regression of subject parameters (gender, age, height, weight, heart rate (HR), brachial systolic pressure (BSP), diastolic pressure (BDP), mean pressure (MP)). Method 2: PPA was calculated from central aortic pressure waveforms (CW) estimated from the same subject parameters. The sample population (1421 male, 992 female) was selected from a database where aortic pressure was estimated by mathematical transformation of a peripheral (radial) pulse calibrated to sphygmomanometric BSP and BDP. The two methods were consistent in showing HR and MP as the most important parameters to estimate PPA. Correlation coefficients (R2) of 0.48 (method 1) and 0.44 (method 2) were obtained using height, weight, HR, BSP, BDP and age. Inclusion of MP increased R2 to 0.77 (method 1) and 0.71 (method 2). This study shows that databases containing peripheral and central aortic pressure waveforms can be used to construct multiple regression models for PPA estimation. These models could be applied to studies of similar subject groups where peripheral waveforms may not be available.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0967-3334
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
879-89
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Estimation of pressure pulse amplification between aorta and brachial artery using stepwise multiple regression models.
pubmed:affiliation
Graduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW 2052, Australia. f.camacho@unsw.edu.au
pubmed:publicationType
Journal Article