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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-9-21
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pubmed:abstractText |
Vitiligo is a common disease characterized by cutaneous white maculae due to loss of melanocytes. It is a polygenic disease, however, the exact pathogenesis of vitiligo is not yet known. The estrogen receptor (ESR) 1 gene was selected as a candidate gene because some researchers treated vitiligo successfully with the steroid-thyroid hormone mixture containing estrogen. Furthermore ESR was expressed in the melanocytes which have an important role in the pigmentation. The polymorphisms of ESR1 gene in vitiligo patients was not reported yet.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0923-1811
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pubmed:author |
pubmed-author:ChungJoo-HoJH,
pubmed-author:HongMee-SukMS,
pubmed-author:JinSheng-YuSY,
pubmed-author:LeeHee JaeHJ,
pubmed-author:LeeMu-HyoungMH,
pubmed-author:LiGuang-ZheGZ,
pubmed-author:ParkHae-JeongHJ,
pubmed-author:ParkHun-KukHK,
pubmed-author:ParkHyun-HoHH,
pubmed-author:SeoJung-ChulJC,
pubmed-author:YimSung-VinSV
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pubmed:copyrightInfo |
Copyright 2004 Japanese Society for Investigative Dermatology
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pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
181-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15381239-Adolescent,
pubmed-meshheading:15381239-Adult,
pubmed-meshheading:15381239-Estrogen Receptor alpha,
pubmed-meshheading:15381239-Female,
pubmed-meshheading:15381239-Gene Frequency,
pubmed-meshheading:15381239-Humans,
pubmed-meshheading:15381239-Introns,
pubmed-meshheading:15381239-Korea,
pubmed-meshheading:15381239-Male,
pubmed-meshheading:15381239-Middle Aged,
pubmed-meshheading:15381239-Polymorphism, Single Nucleotide,
pubmed-meshheading:15381239-Risk Factors,
pubmed-meshheading:15381239-Vitiligo
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pubmed:year |
2004
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pubmed:articleTitle |
Association of estrogen receptor 1 intron 1 C/T polymorphism in Korean vitiligo patients.
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pubmed:affiliation |
Department of Pharmacology, College of Medicine, Kohwang Medical Research Institute, Kyung Hee University, Seoul 130-701, South Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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