Linked Life Data

15381202

Source:http://linkedlifedata.com/resource/pubmed/id/15381202

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2004-9-21
pubmed:abstractText
A major problem facing islet transplantation is immune destruction of grafts by transplant rejection and autoimmunity. Some success in prolonging graft rejection has been obtained by transducing islets prior to transplantation with adenoviral (Ad) vectors containing CTLA4-Ig and TGFbeta. The purpose of this study was to see if lentiviral (LV) vectors would provide superior results compared with adenoviral vectors.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0966-3274
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
191-200
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:15381202-Adenoviridae, pubmed-meshheading:15381202-Animals, pubmed-meshheading:15381202-Antigens, CD, pubmed-meshheading:15381202-Antigens, Differentiation, pubmed-meshheading:15381202-CTLA-4 Antigen, pubmed-meshheading:15381202-DNA, pubmed-meshheading:15381202-Gene Expression, pubmed-meshheading:15381202-Genetic Vectors, pubmed-meshheading:15381202-Graft Survival, pubmed-meshheading:15381202-Immunoconjugates, pubmed-meshheading:15381202-Immunosuppressive Agents, pubmed-meshheading:15381202-Islets of Langerhans Transplantation, pubmed-meshheading:15381202-Lentivirus, pubmed-meshheading:15381202-Male, pubmed-meshheading:15381202-Mice, pubmed-meshheading:15381202-Mice, Inbred Strains, pubmed-meshheading:15381202-Models, Animal, pubmed-meshheading:15381202-RNA, pubmed-meshheading:15381202-Rats, pubmed-meshheading:15381202-Rats, Sprague-Dawley, pubmed-meshheading:15381202-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:15381202-Transduction, Genetic, pubmed-meshheading:15381202-Transforming Growth Factor beta
pubmed:year
2004
pubmed:articleTitle
Transplantation of islets transduced with CTLA4-Ig and TGFbeta using adenovirus and lentivirus vectors.
pubmed:affiliation
Section on Islet Transplantation and Cell Biology, Joslin Diabetes Center, Harvard Medical School, One Joslin Place, Room 535, Boston, MA 02215, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural