Source:http://linkedlifedata.com/resource/pubmed/id/15381010
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
16
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pubmed:dateCreated |
2004-9-21
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pubmed:abstractText |
Chemical investigations of a microfungus Xylaria sp. isolated from the Australian rainforest tree Glochidion ferdinandi have afforded two new natural products, 2-hydroxy-6-methyl-8-methoxy-9-oxo-9H-xanthene-1-carboxylic acid (1) and 2-hydroxy-6-hydroxymethyl-8-methoxy-9-oxo-9H-xanthene-1-carboxylic acid (2). Compound 1 has previously been synthesised but only partially characterised. Methylation of 1 using diazomethane afforded the crystalline compound 2,8-dimethoxy-6-methyl-9-oxo-9H-xanthene-1-carboxylic acid methyl ester (3), whose structure was determined by single crystal X-ray analysis. This paper reports the full spectroscopic characterisation of compounds 1-3 by NMR, UV, IR and MS data. All compounds were inactive in a brine shrimp lethality assay and several antimicrobial screens.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0031-9422
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2373-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15381010-Ascomycota,
pubmed-meshheading:15381010-Lethal Dose 50,
pubmed-meshheading:15381010-Magnetic Resonance Spectroscopy,
pubmed-meshheading:15381010-Mass Spectrometry,
pubmed-meshheading:15381010-Methylation,
pubmed-meshheading:15381010-Microbial Sensitivity Tests,
pubmed-meshheading:15381010-Microscopy, Ultraviolet,
pubmed-meshheading:15381010-Molecular Structure,
pubmed-meshheading:15381010-Plants, Medicinal,
pubmed-meshheading:15381010-Spectrophotometry, Infrared,
pubmed-meshheading:15381010-Trees,
pubmed-meshheading:15381010-Xanthones
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pubmed:year |
2004
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pubmed:articleTitle |
Xanthones from a microfungus of the genus Xylaria.
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pubmed:affiliation |
Chemical Biology Program, Eskitis Institute, Griffith University, Nathan Campus, Brisbane, QLD 4111, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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