Source:http://linkedlifedata.com/resource/pubmed/id/15380745
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2004-9-21
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pubmed:abstractText |
Alphavbeta3 and alphavbeta5 integrins are cell adhesion molecules that play a vital role in tumor angiogenesis and metastasis. The ability to visualize and quantify integrin expression in vivo will foster our understanding of the role of integrins alphavbeta3 and alphavbeta5 in tumor angiogenesis and allow for direct assessment of anti-angiogenic treatment efficacy based on integrin antagonists. This study compared the tumor targeting characteristics of two dimeric 64Cu-labeled RGD peptide agonists of alphavbeta3 integrin.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1536-1632
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
350-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15380745-Animals,
pubmed-meshheading:15380745-Autoradiography,
pubmed-meshheading:15380745-Breast Neoplasms,
pubmed-meshheading:15380745-Copper Radioisotopes,
pubmed-meshheading:15380745-Dimerization,
pubmed-meshheading:15380745-Female,
pubmed-meshheading:15380745-Humans,
pubmed-meshheading:15380745-Integrin alphaV,
pubmed-meshheading:15380745-Kinetics,
pubmed-meshheading:15380745-Mice,
pubmed-meshheading:15380745-Mice, Nude,
pubmed-meshheading:15380745-Oligopeptides,
pubmed-meshheading:15380745-Positron-Emission Tomography
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pubmed:articleTitle |
MicroPET imaging of breast cancer alphav-integrin expression with 64Cu-labeled dimeric RGD peptides.
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pubmed:affiliation |
PET Imaging Science Center, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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