Source:http://linkedlifedata.com/resource/pubmed/id/15378066
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
2004-9-28
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| pubmed:abstractText |
Thalamic nuclei are thought to funnel sensory information to the brain's primary cortical areas, which in turn transmit signals afresh to higher cortical areas. Here we describe a direct projection in the macaque monkey from the lateral geniculate nucleus (LGN) to the motion-selective middle temporal area (MTor V5), a cortical area not previously considered 'primary'. The constituent neurons are mostly koniocellular, send virtually no collateral axons to primary visual cortex (V1) and equal about 10% of the V1 population innervating MT. This pathway could explain the persistence of motion sensitivity in subjects following injury to V1, suggesting more generally that residual perception after damage in a primary area may arise from sparse thalamic input to 'secondary' cortical areas.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
1097-6256
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
7
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
1123-8
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| pubmed:dateRevised |
2007-11-15
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| pubmed:meshHeading |
pubmed-meshheading:15378066-Animals,
pubmed-meshheading:15378066-Axons,
pubmed-meshheading:15378066-Brain Mapping,
pubmed-meshheading:15378066-Calcium-Calmodulin-Dependent Protein Kinase Type 2,
pubmed-meshheading:15378066-Calcium-Calmodulin-Dependent Protein Kinases,
pubmed-meshheading:15378066-Cholera Toxin,
pubmed-meshheading:15378066-Dendrites,
pubmed-meshheading:15378066-Geniculate Bodies,
pubmed-meshheading:15378066-Immunohistochemistry,
pubmed-meshheading:15378066-Macaca mulatta,
pubmed-meshheading:15378066-Male,
pubmed-meshheading:15378066-Motion Perception,
pubmed-meshheading:15378066-Neuronal Plasticity,
pubmed-meshheading:15378066-Neurons,
pubmed-meshheading:15378066-Temporal Lobe,
pubmed-meshheading:15378066-Vision, Low,
pubmed-meshheading:15378066-Visual Cortex,
pubmed-meshheading:15378066-Visual Pathways
|
| pubmed:year |
2004
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| pubmed:articleTitle |
Bypassing V1: a direct geniculate input to area MT.
|
| pubmed:affiliation |
Beckman Vision Center, University of California, 10 Koret Way, San Francisco, California 94143, USA. sincich@itsa.ucsf.edu <sincich@itsa.ucsf.edu>
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| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|