Source:http://linkedlifedata.com/resource/pubmed/id/15375494
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2004-9-17
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pubmed:abstractText |
Prediction of the recurrence of primary breast cancer was attempted by detection of occult neoplastic cells (ONCs) in lymph nodes or by using the high-risk criteria for recurrence/metastasis of gastric and colorectal cancer. The subjects were 70 patients with stage I or II node-negative primary breast cancer. Prediction of recurrence using ONCs had a sensitivity of 60.0% (3/5) and a false-negative rate of 40.0% (2/5) in the recurrence group, while the specificity was 96.9% (63/65) and the false-positive rate was 3.1% (2/65) in the non-recurrence group. The accuracy of ONCs was 78.5%. Prediction of recurrence based on positivity for at least 2 of the high-risk criteria showed a sensitivity of 60.0% (3/5) and a false-negative rate of 40.0% (2/5) in the recurrence group, while the specificity was 95.4% (62/65) and the false-positive rate was 4.6% (3/65) in the non-recurrence group. The accuracy of the high-risk criteria was 77.7%. These results suggest that ONCs show the same accuracy as the high-risk criteria for predicting recurrence/metastasis of stage I and II node-negative breast cancer with a high specificity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1021-335X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
745-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15375494-Breast Neoplasms,
pubmed-meshheading:15375494-Female,
pubmed-meshheading:15375494-Humans,
pubmed-meshheading:15375494-Lymphatic Metastasis,
pubmed-meshheading:15375494-Neoplasm Recurrence, Local,
pubmed-meshheading:15375494-Neoplasm Staging,
pubmed-meshheading:15375494-Neoplastic Cells, Circulating,
pubmed-meshheading:15375494-Occult Blood,
pubmed-meshheading:15375494-Predictive Value of Tests,
pubmed-meshheading:15375494-Risk Factors,
pubmed-meshheading:15375494-Sensitivity and Specificity
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pubmed:year |
2004
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pubmed:articleTitle |
Predicting the recurrence/metastasis of stage I and II breast cancer without lymph node metastasis.
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pubmed:affiliation |
Department of Surgery, Tokai University Oiso Hospital, Kanagawa 259-0198, Japan. onc-res@oiso.u-tokai.ac.jp onc-res@oiso.u-tokai.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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