Linked Life Data

15374608

Source:http://linkedlifedata.com/resource/pubmed/id/15374608

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2004-9-17
pubmed:abstractText
Aqueous leaves extract of Acanthus montanus (Nees) T. Anderson (Acanthaceae) were tested for antiinflammatory, analgesic and antipyretic properties. This was done using standard methodologies following oral administration of the extract. The results showed that the extract significantly reduced the oedema induced by carrageenan within 30 min with 200 mg/kg being the most potent. On the analgesia front, acetic acid writhing test was significant. The extract reduced only the number of paw licks of phase 2 and not phase 1 of formalin test. The results on hotplate and tail immersion tests excluded central acting analgesic properties of the extract. In overall, the analgesic tests conducted revealed that the extract had only peripheral analgesic properties. Its effect on pyresis was also observed to be appreciable. It significantly reduced fever at doses greater than 100 mg/kg within 6 h.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0378-8741
pubmed:author
pubmed:issnType
Print
pubmed:volume
95
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
63-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Antiinflammatory, lack of central analgesia and antipyretic properties of Acanthus montanus (Ness) T. Anderson.
pubmed:affiliation
Department of Physiological Sciences, Faculty of Medicine and Biomedical Sciences, Pharmacology and Toxicology Unit, University of Yaounde 1, Yaounde, Cameroon, P.O. Box 8283, Yaounde. cpehw@yahoo.com
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't