Linked Life Data

15370613

Source:http://linkedlifedata.com/resource/pubmed/id/15370613

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2004-9-16
pubmed:abstractText
Since 2001, 50 breast cancer patients, for whom extensive lung/heart involvement was expected from the use of conventional tangential 2-field technique (2F) owing to complex anatomies, were irradiated using a 3-field conformal technique (3F). Dose plans were designed for both 3F and 2F and a dose volume histogram analysis on ipsilateral lung, heart, and target was conducted. The 3F technique allowed a significant reduction in ipsilateral lung irradiation: mean dose dropped from 16.0+/-3.8 (2F) to 12.0+/-2.7 Gy (3F) and V(45Gy) from 20.7+/-6.8 (2F) to 3.2+/-2.9% (3F). Similarly, in patients irradiated to the left breast, heart mean dose was reduced from 8.1 Gy (2F) to 6.8 Gy (3F) and D(15%) from 19.0 Gy to 14.0 Gy. All differences reached a high degree of significance. The target coverage was not clinically compromised since the slight reduction using 3F compared with 2F is limited to V(95%) while V(90%) difference, even if statistically significant, is small: 98.2+/-1.8% (3F) and 98.8+/-1.6 (2F). A preliminary report on clinical follow up is also included; with a mean follow up of 15.8 months, no pulmonary or cardiac complications were observed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0284-186X
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
558-66
pubmed:dateRevised
2009-5-12
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Breast irradiation with three conformal photon fields for patients with high lung involvement.
pubmed:affiliation
Medical Physics Unit, Department of Physics Oncology, Institute of Southern Switzerland, University of Milan, Bellinzona, Switzerland. lucozzi@iosi.ch
pubmed:publicationType
Journal Article, Clinical Trial