Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2004-9-16
pubmed:abstractText
Nothing is known about haemostasis in Xenarthra, a widely distributed Order of American mammalians. Chaetophractus villosus, a member of the Dasypodidae family of this group, which is easily adapted to captivity, is of growing interest for biomedical research. In this work, we studied platelet number, MPV, ultrastructure of the platelets by SEM and TEM, and aggregation responses to ADP and ristocetin in this species. Blood samples were obtained by cardiac puncture in 20 anaesthetised animals. Platelet count and MPV were evaluated at the beginning and at the end of a 3-year experimental period, to detect possible variations related to time of captivity. SEM and TEM were done by routine methods adapted to the material, and aggregation response to ADP and ristocetin were evaluated by the Born method. The parameters studied did not show any sex-related differences, nor did the platelet count change during captivity. Nevertheless, MPV decreased during this period. Platelets were ultrastructurally similar to those of other mammals and human beings and responded to proven agonists. Data provided in this study will contribute to the understanding of the haemostatic process in this species.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0953-7104
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
279-85
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
A study of platelets in the armadillo chaetophractus villosus (xenarthra, dasypodidae).
pubmed:affiliation
Cátedra de Fisiología Animal, Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional de Sur, San Juan, Bahía Blanca, Argentina.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't